The NVIDIA RTX 4080 SUPER is the objective winner of this comparison, securing a lead in ten out of fourteen measured specifications. Its most significant advantage over the NVIDIA RTX 5070 Ti Mobile is its FP32 performance, which is 100% better. This substantial lead in raw computational capability establishes the desktop card as the superior option for users prioritizing maximum processing power and technical throughput in their hardware configuration.

Choose the NVIDIA RTX 4080 SUPER if you require the highest level of FP32 performance for demanding tasks. Conversely, select the NVIDIA RTX 5070 Ti Mobile if your primary priority is the MSRP, where it holds a 100% advantage over the alternative. Your decision should depend on whether you value the raw computational superiority of the desktop component or the specific financial benefit offered by the mobile unit.