The Western Digital WD Black SN8100 4TB is the objective winner of this comparison, securing more individual specification victories than its competitor. While the Samsung 990 EVO Plus 4TB offers a notable advantage in MSRP, which is 49% better, the Western Digital WD Black SN8100 4TB provides a significantly more powerful performance profile. Its most impactful advantage is a sequential write speed that is 122% better than the alternative, establishing it as the superior option for high-performance tasks.

Users who prioritize raw write performance for demanding workloads should choose the Western Digital WD Black SN8100 4TB to take advantage of its superior sequential write capabilities. Conversely, the Samsung 990 EVO Plus 4TB is the better choice for budget-conscious buyers who want to maximize their storage capacity while benefiting from a 49% better MSRP. Selecting between these two drives depends entirely on whether your priority is achieving maximum write speeds or minimizing your initial investment.