The Samsung 9100 Pro 4TB is the objective winner, securing victories in six out of seven comparable specifications. Its most significant advantage is a sequential read speed that is 187% better than the alternative. This substantial performance lead establishes it as the superior option for users prioritizing raw data throughput and high-capacity storage capabilities. The Western Digital WD Blue SN5000 2TB only outperforms its competitor in a single category, which is its MSRP.

Choose the Samsung 9100 Pro 4TB if your primary requirement is maximum speed and storage volume for demanding professional workloads or high-performance computing tasks. Conversely, the Western Digital WD Blue SN5000 2TB is the logical selection for budget-conscious buyers, as it offers an 82% better MSRP. Opt for this drive if your priority is minimizing initial expenditure rather than achieving the highest possible sequential read performance or total capacity.