The Samsung 9100 Pro 4TB is the objective winner of this comparison, securing victories in five out of seven measured specifications. Its most significant advantage over the alternative is its storage capacity, which is 100% greater. By offering double the space of the Samsung 990 Pro 2TB, the larger drive provides a substantial increase in total data volume for high-capacity storage needs.

Users who prioritize maximum storage space should select the Samsung 9100 Pro 4TB to take advantage of its superior capacity. Conversely, those who are more concerned with the initial cost of the component should choose the Samsung 990 Pro 2TB, as it holds a 65% advantage in MSRP. This makes the smaller drive the more economical choice for buyers who do not require the extensive storage footprint offered by the larger model.