The Samsung 9100 Pro 4TB is the objective winner of this comparison, securing victory in five out of seven measured specifications. Its most significant technical advantage is its sequential write performance, which is 163% better than that of the alternative. This substantial lead in write capability establishes the 4TB model as the superior option for users prioritizing raw data throughput and high-capacity storage performance over other considerations.

Users who require maximum write speeds and the largest available storage capacity should choose the Samsung 9100 Pro 4TB. Conversely, the Samsung 980 Pro 2TB is the better choice for budget-conscious buyers, as it holds a 58% advantage in MSRP. Selecting between these two drives depends entirely on whether your primary requirement is the high-performance throughput of the 4TB model or the cost efficiency offered by the 2TB version.