The Samsung 9100 Pro 4TB is the objective winner of this comparison, securing victory in four out of six measured specifications. Its most significant advantage is its sequential read speed, which outperforms the Samsung 870 EVO 500GB by 2543 percent. While the smaller drive maintains a lead in one category and ties in another, the substantial performance gap in data retrieval makes the larger drive the superior technical option for high-demand storage tasks.

Users prioritizing maximum performance and capacity should choose the Samsung 9100 Pro 4TB to leverage its massive sequential read advantage. Conversely, the Samsung 870 EVO 500GB is the logical choice for budget-conscious buyers, as it offers a 92 percent better MSRP. Select the former for intensive data operations where speed is critical, or opt for the latter if minimizing initial expenditure is the primary requirement for your storage configuration.