The Samsung 990 Pro 4TB is the objective winner of this comparison, securing victory in four out of six evaluated categories. Its most significant technical advantage is its sequential write speed, which outperforms the alternative by 1253%. While the Crucial MX500 2TB holds a lead in MSRP, offering a 71% better value in that specific metric, the superior performance capabilities of the Samsung 990 Pro 4TB make it the clear leader in raw technical output.

Users who prioritize maximum storage capacity and high-speed sequential write performance should choose the Samsung 990 Pro 4TB for their system. Conversely, the Crucial MX500 2TB is the appropriate selection for budget-conscious builders who value a lower MSRP over the high-performance metrics found in the competing drive. Your final decision should depend on whether your primary requirement is the significant speed advantage of the former or the cost efficiency of the latter.