The Gigabyte B660M DS3H DDR4 is the objective winner of this comparison, securing more total specification victories across the evaluated fields. While both motherboards offer distinct benefits, the most impactful advantage for the Gigabyte B660M DS3H DDR4 is its memory slot configuration, which provides a 100% increase in capacity compared to the ASUS ROG STRIX B650E-I GAMING WIFI. This hardware layout serves as the primary differentiator between the two competing component options.

Users who prioritize system memory capacity should select the Gigabyte B660M DS3H DDR4 to take advantage of its superior slot count. Conversely, those who require enhanced connectivity should choose the ASUS ROG STRIX B650E-I GAMING WIFI, as it offers a 100% improvement in USB Type-C capabilities. Your final decision should depend on whether your specific build requirements lean toward expanded memory support or the increased availability of high-speed peripheral ports.