The NVIDIA RTX 4080 SUPER is the objective winner of this comparison, securing victory in ten of the fifteen evaluated categories. While the NVIDIA RTX 2080 SUPER maintains a notable lead in memory clock speed, which is 35% better than its successor, the newer card dominates in raw computational power. The most impactful advantage of the NVIDIA RTX 4080 SUPER is its FP32 performance, which is 368% better than that of the NVIDIA RTX 2080 SUPER.

Users prioritizing raw computational throughput should choose the NVIDIA RTX 4080 SUPER, as its massive lead in FP32 performance makes it the superior option for demanding tasks. Conversely, the NVIDIA RTX 2080 SUPER remains a viable choice for specific workloads that benefit primarily from a higher memory clock. Select the former for modern, high-performance requirements, or opt for the latter if your specific application relies heavily on the memory clock advantage provided by the older architecture.