The NVIDIA RTX 5080 is the objective winner of this comparison, securing victory in ten out of thirteen measured specifications. Its most significant advantage is its FP32 performance, which is 1019% better than that of the NVIDIA GTX 1660. While the older card maintains a lead in three specific areas, the massive leap in raw computational power makes the newer model the clear technical superior in this head-to-head evaluation.

Users prioritizing maximum computational throughput should choose the NVIDIA RTX 5080 to leverage its substantial performance gains. Conversely, the NVIDIA GTX 1660 remains the appropriate selection for buyers who prioritize a lower MSRP, as it offers a 78% advantage in that category. Your final decision should depend on whether your primary requirement is the extreme processing capability of the newer architecture or the cost-focused value proposition of the legacy hardware.