The NVIDIA RTX 4080 is the objective winner of this comparison, securing victory in ten out of thirteen measured specifications. Its most significant advantage over the NVIDIA GTX 1660 is its FP32 performance, which is 869% higher. This massive lead in raw computational capability establishes the former as the superior hardware option across the vast majority of technical categories evaluated in this assessment.

Users prioritizing raw processing power should choose the NVIDIA RTX 4080 to leverage its substantial lead in FP32 performance. Conversely, the NVIDIA GTX 1660 remains the logical choice for buyers focused on the initial MSRP, where it maintains an 82% advantage. Selecting between these two components depends entirely on whether your primary requirement is the high-end computational throughput offered by the newer card or the lower entry cost provided by the older model.