The NVIDIA RTX 4080 is the objective winner of this comparison, securing victories in ten out of thirteen measured specifications. Its most significant advantage over the competition is its FP32 performance, which is 869% better. While the NVIDIA GTX 1660 SUPER holds its own in three specific areas, the sheer scale of the performance gap in raw processing power establishes the newer card as the superior technical option for demanding tasks.

Users prioritizing maximum raw processing power should select the NVIDIA RTX 4080 to leverage its massive lead in FP32 performance. Conversely, those operating under strict budget constraints should choose the NVIDIA GTX 1660 SUPER, as it offers an 81% better MSRP. This choice depends entirely on whether the user requires the highest possible computational output or prefers the significant cost advantage provided by the more affordable hardware option.