The NVIDIA RTX 3090 is the objective winner of this comparison, securing victory in eight out of thirteen measured specifications. Its most significant technical advantage over the NVIDIA GTX 1080 Ti is its FP16 performance, which is 19667% higher. While the older card maintains a lead in four categories, the sheer scale of the performance gap in floating-point operations establishes the newer model as the superior hardware choice based on the provided data.

Users prioritizing raw computational power and the massive advantage in FP16 performance should choose the NVIDIA RTX 3090 for their systems. Conversely, those who are strictly focused on the initial MSRP should select the NVIDIA GTX 1080 Ti, as it holds a 53% advantage in that specific category. Your decision should depend on whether you value the significant leap in processing capabilities or the lower cost associated with the older hardware.