The NVIDIA RTX 3080 Ti is the objective winner of this comparison, securing victory in eight out of thirteen measured specifications. Its most significant technical advantage over the NVIDIA GTX 1080 Ti is its FP16 performance, which is 18844% higher. This massive disparity in computational capability highlights the generational leap in architecture between the two cards, establishing the newer model as the superior option for tasks that rely heavily on high-speed floating-point operations.

Users prioritizing raw computational power and modern architectural efficiency should choose the NVIDIA RTX 3080 Ti for their systems. Conversely, the NVIDIA GTX 1080 Ti remains a viable alternative for budget-conscious builders, as it holds a 42% advantage in MSRP. Those who need to minimize initial hardware expenditure while maintaining functional performance will find the older card more suitable, provided they do not require the extreme FP16 performance gains offered by the newer hardware.