The NVIDIA RTX 3080 is the objective winner of this comparison, securing more total spec victories across the evaluated fields. Its most significant advantage over the NVIDIA GTX 1080 Ti is its FP16 performance, which is 16439% higher. This massive disparity in computational capability represents the primary technical edge held by the newer card, establishing it as the superior option for tasks that rely heavily on this specific metric.

Users prioritizing raw computational throughput should select the NVIDIA RTX 3080 to leverage its substantial FP16 performance lead. Conversely, the NVIDIA GTX 1080 Ti remains a viable choice for those who prioritize power efficiency, as it maintains a 22% advantage in TDP. Choosing between these two components depends on whether your primary requirement is the extreme processing power of the newer architecture or the lower power draw profile offered by the older model.