The NVIDIA RTX 5060 is the objective winner of this comparison, securing victories in nine out of thirteen measured specifications. Its most significant technical advantage over the NVIDIA GTX 1060 6 GB is its FP16 performance, which is 27,300% higher. While the older card maintains a lead in memory bus width, the massive disparity in computational throughput makes the newer hardware the superior choice across the majority of evaluated metrics.

Users prioritizing raw computational power and modern processing capabilities should select the NVIDIA RTX 5060 for its substantial lead in FP16 performance. Conversely, the NVIDIA GTX 1060 6 GB remains a viable option for specific use cases that rely heavily on a wider memory bus, where it retains a 50% advantage. Choose the former for general performance gains or the latter if your specific workload demands the memory bus architecture provided by the older component.