The NVIDIA GTX 1080 is the objective winner of this comparison, securing victory in seven out of twelve measured specifications. Its most significant advantage is its FP32 performance, which is 376% better than that of the alternative. While the NVIDIA GeForce GTX 1050 holds its own in four categories, it cannot match the raw computational power offered by the superior model, which dominates the majority of the technical fields evaluated in this assessment.

Choose the NVIDIA GTX 1080 if your primary requirement is maximum FP32 performance for demanding tasks. Conversely, the NVIDIA GeForce GTX 1050 is the logical selection for users prioritizing a lower MSRP, as it offers an 82% advantage in that specific area. Your decision should depend on whether you value the significant computational lead of the former or the substantial cost-related benefit provided by the latter.