The NVIDIA RTX 5090 is the objective winner of this comparison, securing victory in ten out of fourteen measured specifications. Its most significant advantage over the Intel Arc A380 is its FP32 performance, which is 2395% higher. While the Intel Arc A380 holds its own in three specific areas, the sheer scale of the performance gap in computational capability establishes the NVIDIA RTX 5090 as the superior component based on the provided technical data.

Users prioritizing maximum computational power should choose the NVIDIA RTX 5090 to leverage its massive advantage in FP32 performance. Conversely, the Intel Arc A380 is the logical selection for buyers focused on the MSRP, where it maintains a 94% advantage over the alternative. Your decision should depend on whether your primary requirement is the highest possible processing output or the most favorable initial cost as defined by these specific metrics.