The NVIDIA RTX 3090 is the objective winner of this comparison, securing a lead across the majority of the evaluated technical fields. Its most significant advantage over the AMD RX 6750 XT is its shader unit count, which is 310% higher. While the AMD RX 6750 XT maintains a notable lead in memory clock speed at 85% better, the overall hardware configuration of the NVIDIA RTX 3090 provides a more robust set of specifications for high-end operations.

Users prioritizing raw shader processing power should select the NVIDIA RTX 3090 to leverage its superior unit count. Conversely, the AMD RX 6750 XT is the appropriate choice for those who specifically require the 85% advantage in memory clock speed provided by that card. Your final decision should depend on whether your workload relies more heavily on the extensive shader architecture of the NVIDIA option or the faster memory clock frequency offered by the AMD alternative.