The NVIDIA GeForce RTX 5090D is the objective winner of this comparison, securing victory in nine out of thirteen measured specifications. The most impactful advantage for this card is its shader unit count, which is 963% higher than that of the competition. While the AMD RX 6650 XT holds its own in four specific categories, the sheer scale of the hardware advantage held by the NVIDIA GeForce RTX 5090D makes it the superior choice for raw technical capability.

Users prioritizing budget efficiency should choose the AMD RX 6650 XT, as it offers an 83% advantage in MSRP compared to the alternative. Conversely, those who require the massive increase in shader units provided by the NVIDIA GeForce RTX 5090D should select that component for their build. The decision rests on whether the user values the significant cost savings of the former or the substantial hardware superiority of the latter.