The AMD RX 9060 XT 16 GB is the objective winner of this comparison, securing a lead in eleven out of fifteen measured specifications. While the AMD RX 6650 XT maintains a 21% advantage in base clock speed, the superior card dominates in raw computational power. The most impactful difference between these two components is the FP32 performance, where the AMD RX 9060 XT 16 GB provides a 138% improvement over its counterpart.

Users prioritizing raw computational throughput should select the AMD RX 9060 XT 16 GB to leverage its significant FP32 performance lead. Conversely, the AMD RX 6650 XT remains a viable option for specific use cases that rely heavily on higher base clock speeds. By evaluating these distinct technical advantages, buyers can align their choice with either the high-performance computational capabilities of the newer model or the specific clock frequency profile of the older unit.