The NVIDIA RTX 2080 is the objective winner of this comparison, securing a higher number of superior specifications across the evaluated fields. Its most significant advantage over the competition is its memory bus, which offers a 100% improvement in capacity. While the AMD RX 6600 holds its own in several categories, the overall technical edge remains with the NVIDIA RTX 2080 due to its broader range of superior hardware metrics.

Users prioritizing raw memory bus performance should select the NVIDIA RTX 2080 to leverage its substantial advantage in that specific area. Conversely, those focused on the most favorable MSRP should choose the AMD RX 6600, as it provides a 53% improvement in that category. Your final decision should depend on whether you value the expanded memory bus capabilities of the former or the significant MSRP advantage offered by the latter.