The AMD RX 6600 is the objective winner of this comparison, securing victories in eight out of thirteen measured categories. Its most significant advantage over the NVIDIA GTX 1660 is its FP32 performance, which is 78% higher. This substantial lead in raw computational capability establishes the AMD RX 6600 as the superior option for users prioritizing modern processing power and overall hardware efficiency across the majority of the evaluated technical specifications.

Users should choose the AMD RX 6600 if they require the highest FP32 performance for their computing tasks. Conversely, the NVIDIA GTX 1660 remains a viable alternative for specific workloads that benefit from its memory bus, which is 50% wider than that of its competitor. Selecting between these two components depends entirely on whether your primary requirement is the superior computational throughput of the AMD RX 6600 or the memory bus advantage offered by the NVIDIA GTX 1660.