The AMD RX 590 is the objective winner of this comparison, securing six spec victories compared to the single win held by the AMD RX 580. The most impactful advantage for the newer card is its base clock speed, which provides a 17% improvement over the older model. While the AMD RX 580 maintains a 29% advantage in MSRP, the superior clock speed of the AMD RX 590 makes it the more capable option across the majority of measured specifications.

Users prioritizing raw clock speed and overall technical specifications should choose the AMD RX 590 for its clear performance-based advantages. Conversely, those who are strictly focused on the MSRP benefit should opt for the AMD RX 580. Because the two components tied in six categories, the decision rests on whether the buyer values the 17% base clock increase found in the AMD RX 590 or the 29% MSRP advantage offered by the AMD RX 580.