The NVIDIA RTX 5090 is the objective winner of this comparison, securing victory in ten out of thirteen measured specifications. Its most significant advantage is its FP32 performance, which is 1698% better than that of the AMD RX 480. While the latter component holds a lead in three specific categories, the sheer scale of the performance gap in computational throughput establishes the former as the superior hardware option based on the provided technical data.

Users prioritizing raw computational power should choose the NVIDIA RTX 5090 to leverage its massive lead in FP32 performance. Conversely, the AMD RX 480 is the appropriate selection for buyers who prioritize the MSRP advantage, which is 90% better than the alternative. By focusing on these specific strengths, consumers can align their purchase with either the high-performance capabilities of the newer card or the cost-focused benefits offered by the older model.