The AMD RX 6800 is the objective winner of this comparison, securing victory in eight of the thirteen evaluated categories. Its most significant technical advantage is its FP16 performance, which is 455% better than that of the alternative. While the AMD RX 480 remains competitive in specific areas, it falls behind in the majority of technical specifications, ultimately failing to match the superior processing capabilities offered by the newer hardware.

Users prioritizing raw computational power should select the AMD RX 6800 to leverage its substantial lead in FP16 performance. Conversely, the AMD RX 480 is the appropriate choice for budget-conscious buyers, as it holds a 66% advantage in MSRP. Choosing between these two components depends entirely on whether your primary requirement is the high-end processing capacity of the newer model or the cost-effective positioning of the older unit.