The AMD RX 6750 XT is the objective winner of this comparison, securing nine spec victories compared to the three held by the AMD RX 480. The most significant technical advantage for the newer card is its FP16 performance, which is 357% better than that of its predecessor. This substantial lead in computational capability establishes the AMD RX 6750 XT as the superior hardware option across the majority of the measured technical categories.

Users prioritizing raw computational power and modern specifications should choose the AMD RX 6750 XT to leverage its massive advantage in FP16 performance. Conversely, the AMD RX 480 remains a viable selection for budget-conscious buyers who prioritize its 64% better MSRP. Selecting between these two components depends entirely on whether a user values the significantly higher performance ceiling of the newer model or the lower initial cost of the older hardware.