The AMD RX 480 and the AMD RX 5500 XT are tied in this objective comparison, as each component leads in six distinct technical specifications. The most significant advantage for the AMD RX 480 is its VRAM capacity, which is 100% higher than that of its counterpart. Conversely, the AMD RX 5500 XT holds a substantial lead in computational efficiency, offering FP16 performance that is 78% higher than the performance provided by the AMD RX 480.

Users who prioritize memory capacity for their specific workloads should select the AMD RX 480 to leverage its superior VRAM. Those who require higher FP16 performance for specialized computational tasks should choose the AMD RX 5500 XT instead. Because these components are evenly matched across the majority of measured specifications, the final decision depends entirely on whether your workflow benefits more from the increased memory of the former or the enhanced computational speed of the latter.