The Intel Core Ultra 5 245KF is the objective winner of this comparison, securing more category victories across the evaluated specifications. While both processors offer distinct strengths, the most impactful advantage belongs to the Intel Core Ultra 5 245KF, which delivers 100% better NPU performance compared to its counterpart. This significant lead in specialized processing capability establishes the newer model as the superior choice for modern workloads that rely on integrated neural processing hardware.

Users prioritizing heavy multitasking and parallel processing should select the Intel Core i9-12900K, as it maintains a 71% advantage in thread count. Conversely, those focused on leveraging advanced AI-driven features and modern neural processing tasks should opt for the Intel Core Ultra 5 245KF. Choosing between these two components depends entirely on whether your specific workflow demands the higher thread capacity of the former or the enhanced NPU capabilities of the latter.