The Intel Core Ultra 5 245KF is the objective winner of this comparison, securing victories in eleven out of fourteen measured specifications. While the Intel Core i9-10900K maintains a significant lead in thread count, offering 43% more threads than its counterpart, the newer model dominates in cache architecture. The most impactful advantage for the Intel Core Ultra 5 245KF is its L2 cache, which is 940% larger than that found in the Intel Core i9-10900K.

Users who prioritize high thread counts for specific multi-threaded workloads should select the Intel Core i9-10900K for its superior capacity in that area. Conversely, the Intel Core Ultra 5 245KF is the better choice for those who benefit from the massive L2 cache advantage and the broader range of technical improvements across the majority of measured specifications. Choosing between them depends on whether your primary requirement is raw thread volume or the architectural benefits of the newer cache design.