The Intel Core Ultra 5 250KF Plus wins in 10 out of 16 comparable specs, with 3 ties. Its biggest advantage is L2 Cache (300% better).
Core i5-12400F wins in 3 specs (TDP: 48% better).
Recommendation
Choose Core Ultra 5 250KF Plus if you want the best overall performance — especially l2 cache.
Choose Core i5-12400F if tdp matters more to you.
