The Arctic Liquid Freezer III 280 and the Arctic Liquid Freezer III 420 represent a tie in this objective comparison, as each component secures two spec wins. The primary advantage for the smaller unit is its MSRP, which is 14% better than the larger model. Conversely, the most impactful advantage for the larger cooler is its radiator size, which is 50% better than the 280mm version, providing a significant difference in physical dimensions.

Choose the Arctic Liquid Freezer III 280 if you prioritize a lower MSRP and need a more compact radiator size for your build. Select the Arctic Liquid Freezer III 420 if your primary requirement is the 50% larger radiator size, which offers a substantial increase in surface area. Your decision should depend on whether you value the cost efficiency of the smaller model or the increased physical capacity of the larger one.