The Thermaltake CTE C750 Air is the objective winner of this comparison, securing five spec victories against two for the Thermaltake S100 TG. The most impactful advantage for the Thermaltake CTE C750 Air is its included fan configuration, which offers a 200% improvement over the alternative. This superior cooling hardware provides a significant edge in out-of-the-box thermal potential, making it the more robust choice for users prioritizing integrated airflow components for their system builds.

Users who require a high-capacity chassis with extensive cooling support should select the Thermaltake CTE C750 Air to leverage its fan advantage. Conversely, the Thermaltake S100 TG is the better option for budget-conscious builders, as it holds a 74% advantage in MSRP. Choosing between these two cases depends on whether your priority is maximizing the value of included cooling hardware or minimizing the initial financial investment required for your PC enclosure.