The Lian Li Lancool 216 is the objective winner of this comparison, securing victories in six out of eight evaluated specifications. Its most significant advantage lies in the included fans, which offer a 200% improvement over the competition. This superior cooling configuration establishes the Lian Li Lancool 216 as the more robust option for users prioritizing airflow and thermal management out of the box.

Users who require high-performance cooling should select the Lian Li Lancool 216 for its substantial fan advantage. Conversely, the Thermaltake S100 TG is the better choice for those who prioritize storage capacity, as it provides a 50% advantage in 2.5" drive bays. Choosing between these cases depends entirely on whether your build demands optimized airflow or increased space for secondary storage drives.