The Corsair 4000D RS Frame is the objective winner of this comparison, securing more category wins across the evaluated specifications. Its most significant advantage is a 9% increase in maximum GPU length compared to the alternative, providing more flexibility for users installing larger graphics cards. While both cases share several identical specifications, the Corsair 4000D RS Frame offers superior physical clearance for high-end hardware components, making it the more versatile choice for builds requiring extensive internal space.

Users prioritizing maximum GPU compatibility should select the Corsair 4000D RS Frame to ensure their graphics card fits without restriction. Conversely, the Fractal Design Meshify 2 Compact is the better option for storage-heavy builds, as it provides a 100% advantage in the number of available 2.5-inch drive bays. Choosing between these two cases depends entirely on whether your specific build configuration requires additional room for a large graphics card or increased capacity for smaller storage drives.