The Fractal Design Meshify 2 Compact is the objective winner of this comparison, securing more category victories than the ASUS Prime AP201. The most significant advantage offered by the Fractal Design Meshify 2 Compact is its superior cooling configuration, as it provides 100% more included fans than its competitor. While the ASUS Prime AP201 remains a viable alternative, it falls behind in overall hardware specifications despite its notable 25% advantage in MSRP.

Users prioritizing out-of-the-box thermal performance and a more comprehensive cooling setup should choose the Fractal Design Meshify 2 Compact. Conversely, the ASUS Prime AP201 is the better option for budget-conscious builders who want to minimize their initial expenditure. By selecting based on these specific advantages, you can align your purchase with either a focus on immediate cooling utility or a preference for a lower upfront cost.